منابع مشابه
Shifting Sugars and Shifting Paradigms
No organism lives in a constant environment. Based on classical studies in molecular biology, many have viewed microbes as following strict rules for shifting their metabolic activities when prevailing conditions change. For example, students learn that the bacterium Escherichia coli makes proteins for digesting lactose only when lactose is available and glucose, a better sugar, is not. However...
متن کاملShifting paradigms in Hedgehog signaling.
Hedgehog (Hh) signaling proteins regulate multiple developmental and adult homeostatic processes. A defining feature of Hh signaling is that relatively small changes in the concentration of Hh ligand elicit dramatically different cellular responses. As a result, the processing, release and trafficking of Hh ligands must be tightly regulated to ensure proper signaling. In addition, sensitive and...
متن کاملShifting Paradigms in Island Biology
The ease of travel by jet aircraft has opened up island areas not only for study but also for introduction of weeds, pests, and pathogens. We are at a critical juncture in the study of island organisms, which have become more accessible at the same time that they are vanishing. With the urgency for study of island organisms, we have many new tools, especially molecular ones, which have validate...
متن کاملShifting Paradigms with the Application Service Provider Model
I n the past four decades, several technological breakthroughs have made it feasible to sell computing as a service rather than a product. Supercomputers and clustering technologies have made huge amounts of raw computing power available, while time-sharing operating systems have made computing resources a divisible utility. Personal computers have educated generations of home and office comput...
متن کاملEmerging Viruses in the Felidae: Shifting Paradigms
The domestic cat is afflicted with multiple viruses that serve as powerful models for human disease including cancers, SARS and HIV/AIDS. Cat viruses that cause these diseases have been studied for decades revealing detailed insight concerning transmission, virulence, origins and pathogenesis. Here we review recent genetic advances that have questioned traditional wisdom regarding the origins o...
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ژورنال
عنوان ژورنال: GATESOL in Action Journal
سال: 2016
ISSN: 2331-6845
DOI: 10.52242/giaj.v26i1.44